Rumination-Focused Cognitive Behavioral Therapy Reduces Rumination and Targeted Cross-network Connectivity in Youth With a History of Depression: Replication in a Preregistered Randomized Clinical Trial.

ABSTRACT:

Background

Rumination-focused cognitive behavioral therapy (RF-CBT) is designed to reduce depressive rumination or the habitual tendency to dwell on experiences in a repetitive, negative, passive, and global manner. RF-CBT uses functional analysis, experiential exercises, and repeated practice to identify and change the ruminative habit. This preregistered randomized clinical trial (NCT03859297, R61) is a preregistered replication of initial work. We hypothesized a concurrent reduction of both self-reported rumination and cross-network connectivity between the left posterior cingulate cortex and right inferior frontal and inferior temporal gyri.

Methods

Seventy-six youths with a history of depression and elevated rumination were randomized to 10 to 14 sessions of RF-CBT (

SUBMITTER: Langenecker SA 

PROVIDER: S-EPMC10654545 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature