Chemotherapy-Related Amenorrhea and Quality of Life Among Premenopausal Women With Breast Cancer.

ABSTRACT:

Importance

Younger survivors of breast cancer frequently report more treatment-related symptoms, mostly related to the menopausal transition.

Objective

To assess factors associated with chemotherapy-related amenorrhea (CRA) and to evaluate its association with long-term quality of life (QOL).

Design, setting, and participants

The prospective, longitudinal Cancer Toxicities Study, a multicenter French cohort study, includes women with a diagnosis of stage I to III breast cancer and collects data approximately yearly after diagnosis. The current study reports outcomes up to 4 years after diagnosis for participants enrolled from 2012 to 2017. Participants included premenopausal women younger than 50 years treated with chemotherapy and not receiving adjuvant ovarian funct

SUBMITTER: Kabirian R 

PROVIDER: S-EPMC10654794 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature