Degree of Albuminuria is Associated With Increased Risk of Fragility Fractures Independent of Estimated GFR.

ABSTRACT:

Introduction

Fragility fractures are common in persons with chronic kidney disease (CKD); however, the association between fragility fractures and albuminuria is not well-studied. The primary objective of this study is to determine the association of albuminuria with incident risk of fragility fractures. The secondary objective is to examine the risk of fragility fracture by estimated glomerular filtration rate (eGFR) and Kidney Disease Improving Global Outcomes (KDIGO) risk categories.

Methods

Community dwelling adults residing in Alberta, Canada who had at least 1 creatinine and albuminuria measurement between April 1, 2008 and March 31, 2019 participated in the study (N = 2.72 million). Incident fragility fractures were identified using Canadian Chronic Disease Sur

SUBMITTER: Cooke-Hubley SM 

PROVIDER: S-EPMC10658242 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature