Inhibitory effects of Bacillus velezensis ID-A01 supernatant against Streptococcus mutans.

ABSTRACT:

Background

Dental caries is a chronic oral disease caused by microbial infections, which result in erosion of the dental enamel and cause irreversible damage. Therefore, proper disease management techniques and the creation of an environment that prevents intraoral growth and biofilm formation of Streptococcus mutans in the early stages, are crucial to prevent the potential progression of dental plaque to disease. Here, we aimed to investigate antimicrobial and antibiofilm effects of the Bacillus velezensis ID-A01 supernatant (ID23029) against S. mutans, and its inhibitory effects on acidogenesis.

Results

A killing kinetics assay showed a peak lethality percentage of 94.5% after 6 h of exposure to ID23029. In sucrose-exposed conditions, ID23029 inhibited lactic acid formatio

SUBMITTER: Kim H 

PROVIDER: S-EPMC10668352 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature