The landscape of investigator-initiated oncology trials conducted in mainland China during the past decade (2010-2019).

ABSTRACT: The number of clinical trials conducted in mainland China, including investigator-initiated trials (IITs), has increased rapidly in recent years. However, there are few data on the characteristics of cancer-related IITs. We performed a comprehensive analysis of the landscape of cancer-related IITs in mainland China in the past decade. All cancer-related IITs registered on two clinical trial registries in the United States (www.clinicaltrials.gov, CT.gov) and mainland China (www.chictr.org.cn, ChiCTR) from 2010 to 2019 were identified. IITs were reviewed manually to validate classification, subcategorized by cancer type, and stratified by design characteristics to facilitate comparison across cancer types and with other specialties. A total of 8199 cancer-related IITs were identified. The n

SUBMITTER: Cao Y 

PROVIDER: S-EPMC10686146 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature