National Danish surveillance of invasive clinical Haemophilus influenzae isolates and their resistance profile.

ABSTRACT:

Introduction

This study aimed to investigate the epidemiology, serotype distribution, phenotypical antibiogram, and molecular resistance gene characteristics of invasive Haemophilus influenzae infections in Denmark from 2014 to 2022. Additionally, the potential impact of outdoor temperature and COVID-19 restrictions on the epidemiology of H. influenzae was assessed.

Materials and methods

Invasive H. influenzae isolates were received from patients with positive culture results from cerebrospinal fluid, blood, or other sterile sites. Sample data were obtained from the Danish laboratory surveillance system/MiBa database, and whole-genome sequencing (WGS) was performed on the isolates. The incidence rates and distribution of H. influenzae cases were a

SUBMITTER: Slotved HC 

PROVIDER: S-EPMC10702724 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature