Effects of probiotics on neurocognitive outcomes in infants and young children: a meta-analysis.

ABSTRACT:

Background

Therapeutic efficacies of probiotics in improving neurocognitive functions in infants and young children remained unclear. This meta-analysis focused on different cognitive outcomes in this population.

Methods

Major databases were searched electronically from inception to October 2023 to identify randomized controlled trials (RCTs) that investigated the therapeutic efficacy of probiotics in enhancing cognitive functions assessed by standardized tasks. The overall effect size was calculated as standardized mean difference (SMD) based on a random effects model.

Results

Nine RCTs with 3,026 participants were identified. Both our primary and secondary results demonstrated no significant difference in neurocognitive outcomes between infants/children treated with

SUBMITTER: Lin FL 

PROVIDER: S-EPMC10728653 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature