Molecular characterization of IncFII plasmid carrying bla_NDM-5 in a Salmonella enterica serovar Typhimurium ST34 clinical isolate in China.

ABSTRACT:

Importance

In this study, an IncFII plasmid pIncFII-NDM5 carrying bla_NDM-5 was found in carbapenem-resistant Salmonella enterica serovar Typhimurium (S. enterica serovar Typhimurium), which has conjugative transferability and carried bla_NDM-5, ble_MBL, mph(A), and bla_TEM-1 four resistance genes that can mediate resistance to multiple antibiotics including cephalosporins, beta-lactamase inhibitor combinations, carbapenems, and macrolides. Phylogenetic analysis showed that 1104-65 and 1104-75 were closely related to other S. enterica serovar Typhimurium in this area. The above-mentioned S. enterica serovar Typhimurium chromosome carries bla_CTX-M-55, qnrS1

SUBMITTER: Zeng S 

PROVIDER: S-EPMC10732066 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature