Effects of Genes, Lifestyles, and Noise Kurtosis on Noise-Induced Hearing Loss.

ABSTRACT:

Objective

To explore the association of lifestyles, caspase gene (CASP), and noise kurtosis with noise-induced hearing loss (NIHL).

Design

Three hundred seven NIHL individuals and 307 matched controls from factories in Chinese factories participated in this case-control study. Age, sex, noise exposure, exfoliated oral mucosa cells, and lifestyles of participants were gathered by the authors. The single nucleotide polymorphisms (SNPs) were genotyped using the Kompetitive Allele Specific polymerase chain reaction (KASP) method.

Results

The risk of NIHL was higher for people who worked in the complex noise environment than for people exposed to steady noise environment (adjusted: OR = 1.806, P = 0.002). Smoking and regular earphone use increased the risk of NIHL (adjuste

SUBMITTER: Yin X 

PROVIDER: S-EPMC10747805 | biostudies-literature | 2023 Jul-Sep

REPOSITORIES: biostudies-literature