Traumatic Encephalopathy Syndrome and Tauopathy in a 19-Year-Old With Child Abuse.

ABSTRACT: The majority of traumatic encephalopathy syndrome (TES) cases have been reported in former contact sport athletes. This is the first case with TES in a 19-year-old male patient with progressive cognitive decline after daily domestic physical violence through repeated hits to the head for 15 years. The patient presented with a moderate depressive episode and progressive cognitive decline. Tau positron emission tomography (PET) with 220 MBq of [¹⁸F]PI-2620 revealed increased focal signal at the frontal and parietal white/gray matter border. Brain magnetic resonance imaging (MRI) showed a cavum septum pellucidum, reduced left-sided hippocampal volume, and a left midbrain lesion. Cerebrospinal fluid results showed elevated total and p-tau. Neurocognitive testing at admission showed

SUBMITTER: Rueb M 

PROVIDER: S-EPMC10754342 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature