Association between antithrombotic therapy and mortality in patients hospitalized for COVID‑19.

ABSTRACT:

Background

The prothrombotic state is a common abnormality in patients with coronavirus disease 2019 (COVID-19). However, there is controversy over the use of anticoagulants, especially oral anticoagulants (OAC) due to limited studies. We sought to evaluate the association between antithrombotic therapy on mortality and clinical outcomes in patients hospitalized for COVID-19 through propensity score matching (PSM) analysis.

Methods

A retrospective cohort study was performed to include adult patients with COVID-19 in a university hospital. The primary outcome was in-hospital mortality. Secondary outcomes included intensive care unit (ICU) admission, mechanical ventilation, and acute kidney injury (AKI) during hospitalization. PSM was used as a powerful tool for matching patie

SUBMITTER: Wang X 

PROVIDER: S-EPMC10768353 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature