Competing risk analysis of cardiovascular death in breast cancer: evidence from the SEER database.

ABSTRACT:

Background

Cardiovascular disease (CVD) is the leading cause of death for all non-cancer deaths among breast cancer (BC) patients. The aim of this study was to investigate the risk of cardiovascular mortality (CVM) in patients with BC.

Methods

Patients diagnosed with primary BC between 2010 and 2018 were identified through the Surveillance, Epidemiology and End Results (SEER) database. The standardized mortality ratio (SMR) for CVD was calculated to compare the CVM of BC patients with that of the general population. Multivariate competing risk models were performed to identify predictors of CVM in BC patients.

Results

Overall, 399,014 BC patients were included from the SEER database, of whom 7,023 (1.8%) suffered death from CVD. The significantly higher overall SMR of

SUBMITTER: He J 

PROVIDER: S-EPMC10774043 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature