IS26 drives the dissemination of bla _CTX-M genes in an Ecuadorian community.

ABSTRACT:

Importance

The horizontal gene transfer events are the major contributors to the current spread of CTX-M-encoding genes, the most common extended-spectrum β-lactamase (ESBL), and many clinically crucial antimicrobial resistance (AMR) genes. This study presents evidence of the critical role of IS26 transposable element for the mobility of bla _CTX-M gene among Escherichia coli isolates from children and domestic animals in the community. We suggest that the nucleotide sequences of IS26-bla _CTX-M could be used to study bla _CTX-M transmission between humans, domestic animals, and the environment, because understanding of the dissemination patterns of AMR genes is critical to implement effective measures to slow

SUBMITTER: Salinas L 

PROVIDER: S-EPMC10783052 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature