Effects of sleep deprivation on cortical excitability: A threshold-tracking TMS study and review of the literature.

ABSTRACT:

Objective

Insufficient sleep is linked to several health problems. Previous studies on the effects of sleep deprivation on cortical excitability using conventional transcranial magnetic stimulation (TMS) included a limited number of modalities, and few inter-stimulus intervals (ISIs) and showed conflicting results. This study aimed to investigate the effects of sleep deprivation on cortical excitability through threshold-tracking TMS, using a wide range of protocols at multiple ISIs.

Methods

Fifteen healthy subjects (mean age ± SD: 36 ± 3.34 years) were included. The following tests were performed before and after 24 h of sleep deprivation using semi-automated threshold-tacking TMS protocols: short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF)

SUBMITTER: Mroczek M 

PROVIDER: S-EPMC10787222 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature