Associations between maternal and offspring glucose metabolism: a 9-year follow-up of a randomised controlled trial.

ABSTRACT:

Introduction

There is increasing evidence that the in utero environment affects the health and disease risk of offspring throughout their lives. The long-term effect of maternal hyperglycaemia on offspring glucose metabolism is of interest in a public health perspective. The aim of this study was to examine the association between in utero exposure to maternal glycaemia and offspring glucose metabolism.

Methods

Mother-child pairs were recruited from an RCT to prevent gestational diabetes mellitus where 855 healthy pregnant women were randomised to exercise or standard antenatal care. The original RCT detected no group differences in gestational diabetes mellitus prevalence or insulin resistance. The two groups were analysed as one group in the present study. Ma

SUBMITTER: Nyen SL 

PROVIDER: S-EPMC10806570 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature