Mitochondrial genomes revisited: why do different lineages retain different genes?
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ABSTRACT:
SUBMITTER: Butenko A
PROVIDER: S-EPMC10809612 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Publications
Mitochondrial genomes revisited: why do different lineages retain different genes?
Butenko Anzhelika A Lukeš Julius J Speijer Dave D Wideman Jeremy G JG
BMC biology 20240125 1
The mitochondria contain their own genome derived from an alphaproteobacterial endosymbiont. From thousands of protein-coding genes originally encoded by their ancestor, only between 1 and about 70 are encoded on extant mitochondrial genomes (mitogenomes). Thanks to a dramatically increasing number of sequenced and annotated mitogenomes a coherent picture of why some genes were lost, or relocated to the nucleus, is emerging. In this review, we describe the characteristics of mitochondria-to-nucl ...[more]
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