IL-39 and IL-35 gingival crevicular fluid levels in diabetic patients with generalized periodontitis.

ABSTRACT:

Objectives

This research was performed to investigate if there is a role for IL-39 in immunopathogenesis of both systemically healthy and diabetic periodontitis patients. Additionally, to explore if we can consider IL-39 and IL-35 as biomarkers for periodontitis activity.

Materials and methods

A total of 38 periodontitis patients and 19 control volunteers were included in our study. The periodontitis patients were divided equally into (Group I), 19 patients with stage III grade C periodontitis with diabetes mellitus and (Group II), 19 patients with stage III grade B periodontitis and systemically healthy. Gingival crevicular fluid levels of each interleukin were measured pre- and postoperatively for all periodontitis patients as well as control subjects using ELISA.

Resul

SUBMITTER: Hassan SS 

PROVIDER: S-EPMC10824872 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature