Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Risk stratification is a cornerstone of the Pediatric Infectious Diseases Society COVID-19 treatment guidance. This systematic review and meta-analysis aimed to define the clinical characteristics and comorbidities associated with critical COVID-19 in children and adolescents.

Methods

Two independent reviewers screened the literature (Medline and EMBASE) for studies published through August 2023 that reported outcome data on patients aged ≤21 years with COVID-19. Critical disease was defined as an invasive mechanical ventilation requirement, intensive care unit admission, or death. Random effects models were used to estimate pooled odds ratios (OR) with 95% confidence intervals (CI), and heterogeneity was explored through subgroup analyses.

Results

Among 10

SUBMITTER: Aparicio C 

PROVIDER: S-EPMC10827273 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature