Young-onset colorectal cancer: treatment-related nausea, vomiting and diarrhoea.

ABSTRACT:

Objectives

Early-onset colorectal cancer (EO-CRC) incidence is increasing, raising a clinical challenge. Clinicians tend to treat EO-CRC patients with more intensive regimens despite the lack of survival benefits, based on an age-related bias. Limited evidence is available regarding treatment-related toxicities in this peculiar subset of patients.

Methods

We performed a literature search in MEDLINE/PubMed, EMBASE and Scopus, looking for reporting of nausea, vomiting and diarrhoea occurring in patients with EO-CRC, defined by age lower than 50 years old at initial diagnosis, while receiving anticancer treatment.

Results

2318 records were screened and 9 full-text articles were considered eligible for inclusion for a total of 59 783 patients (of whom 8681 EO-CRC patients

SUBMITTER: Mauri G 

PROVIDER: S-EPMC10850832 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature