Normal or near normal aminotransferase levels in patients with alcoholic cirrhosis.

ABSTRACT:

Background

Alcoholic liver disease is caused by excessive alcohol consumption that results in an inflammatory response and fibrosis. We have recognized that patients with alcoholic cirrhosis often have unremarkable liver enzyme values.

Methods

In this retrospective cohort analysis, we identified consecutive patients with documented alcoholic cirrhosis at an academic medical center who were admitted between January 1 2016 and December 1 2018. We examined clinical outcomes of patients as a function of whether the aspartate transaminase (AST) or alanine aminotransferase (ALT) was normal or abnormal. Likelihood chi-square analyses were utilized for group comparisons and t-tests were used for numerical data.

Results

In the cohort of 78 patients with alcoholic cirrhosis (ag

SUBMITTER: Sullivan MK 

PROVIDER: S-EPMC10860165 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature