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The association between peripheral eosinophil count and chronic kidney disease: evidence from NHANES 1999-2018.


ABSTRACT:

Background

Renal impairment has been previously linked to peripheral eosinophil count (PEC), prompting an investigation into its potential relationship with chronic kidney disease (CKD). This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES 1999-2018) to comprehensively explore the association between PEC and CKD.

Methods

Survey-weighted generalized multivariate linear regression was employed to evaluate the associations between PEC, urinary albumin-to-creatinine ratio (UACR), and estimated glomerular filtration rate (eGFR), with meticulous adjustment for potential covariates. To assess non-linear correlations, a restricted cubic spline analysis was conducted. Sensitivity analysis was performed to test the stability of res

SUBMITTER: Han S 

PROVIDER: S-EPMC10896169 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature