Dataset Information

Dynamics of brain-muscle networks reveal effects of age and somatosensory function on gait.

ABSTRACT: Walking is a complex motor activity that requires coordinated interactions between the sensory and motor systems. We used mobile EEG and EMG to investigate the brain-muscle networks involved in gait control during overground walking in young people, older people, and individuals with Parkinson's disease. Dynamic interactions between the sensorimotor cortices and eight leg muscles within a gait cycle were assessed using multivariate analysis. We identified three distinct brain-muscle networks during a gait cycle. These networks include a bilateral network, a left-lateralized network activated during the left swing phase, and a right-lateralized network active during the right swing. The trajectories of these networks are contracted in older adults, indicating a reduction in neuromuscular connectivity with age. Individuals with the impaired tactile sensitivity of the foot showed a selective enhancement of the bilateral network, possibly reflecting a compensation strategy to maintain gait stability. These findings provide a parsimonious description of interindividual differences in neuromuscular connectivity during gait.

SUBMITTER: Roeder L

PROVIDER: S-EPMC10897916 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature

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Dynamics of brain-muscle networks reveal effects of age and somatosensory function on gait.

Roeder Luisa L Breakspear Michael M Kerr Graham K GK Boonstra Tjeerd W TW

iScience 20240209 3

Walking is a complex motor activity that requires coordinated interactions between the sensory and motor systems. We used mobile EEG and EMG to investigate the brain-muscle networks involved in gait control during overground walking in young people, older people, and individuals with Parkinson's disease. Dynamic interactions between the sensorimotor cortices and eight leg muscles within a gait cycle were assessed using multivariate analysis. We identified three distinct brain-muscle networks dur ...[more]

PMID: 38414847

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Dataset Information

Dynamics of brain-muscle networks reveal effects of age and somatosensory function on gait.

Publications

Dynamics of brain-muscle networks reveal effects of age and somatosensory function on gait.

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