Fetal Sexual Dimorphism and Preeclampsia Among Twin Pregnancies.

ABSTRACT:

Background

In singleton pregnancies, fetal sexual dimorphism has been observed in hypertensive disorders of pregnancy, particularly preeclampsia, a morbid syndrome that increases the risk of adult-onset cardiovascular disease for mothers and their offspring. However, few studies have explored the effect of fetal sex on hypertensive disorders of pregnancy among twin pregnancies.

Methods

We conducted a retrospective cohort study of 1032 twin pregnancies between 2011 and 2022 using data from a perinatal database that recruits participants from 3 hospitals in Houston, TX. We categorized pregnancies based on fetal sex pairings into female/female, male/male, and female/male. Pregnancies with female/female pairs were used as our reference group. Our primary outcomes included gestat

SUBMITTER: Brown RE 

PROVIDER: S-EPMC10922256 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature