Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta-analysis.

ABSTRACT:

Introduction

The extent to which the Big Five personality traits and subjective well-being (SWB) are discriminatory predictors of clinical manifestation of dementia versus dementia-related neuropathology is unclear.

Methods

Using data from eight independent studies (N_total = 44,531; N_dementia = 1703; baseline M_age = 49 to 81 years, 26 to 61% female; M_follow-up range = 3.53 to 21.00 years), Bayesian multilevel models tested whether personality traits and SWB differentially predicted neuropsychological and neuropathological characteristics of dementia.

Results

Synthesized and individual study results indicate that high neuroticism and negative affect and low conscientiousness, extraversion, and positive affect were associated

SUBMITTER: Beck ED 

PROVIDER: S-EPMC10947984 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature