Functional Model of Compound II of Cytochrome P450: Spectroscopic Characterization and Reactivity Studies of a Fe^IV-OH Complex.

ABSTRACT: Herein, we show that the reaction of a mononuclear Fe^III(OH) complex (1) with N-tosyliminobenzyliodinane (PhINTs) resulted in the formation of a Fe^IV(OH) species (3). The obtained complex 3 was characterized by an array of spectroscopic techniques and represented a rare example of a synthetic Fe^IV(OH) complex. The reaction of 1 with the one-electron oxidizing agent was reported to form a ligand-oxidized Fe^III(OH) complex (2). 3 revealed a one-electron reduction potential of -0.22 V vs Fc⁺/Fc at -15 °C, which was 150 mV anodically shifted than 2 (E_red = -0.37 V vs Fc⁺/Fc at -15 °C), inferring 3 to be more oxidizing than 2. 3 reacted

SUBMITTER: Keshari K 

PROVIDER: S-EPMC10976569 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature