From sub-Saharan Africa to China: Evolutionary history and adaptation of <i>Drosophila melanogaster</i> revealed by population genomics.

ABSTRACT: Drosophila melanogaster is a widely used model organism for studying environmental adaptation. However, the genetic diversity of populations in Asia is poorly understood, leaving a notable gap in our knowledge of the global evolution and adaptation of this species. We sequenced genomes of 292 D. melanogaster strains from various ecological settings in China and analyzed them along with previously published genome sequences. We have identified six global genetic ancestry groups, despite the presence of widespread genetic admixture. The strains from China represent a unique ancestry group, although detectable differentiation exists among populations within China. We deciphered the global migration and demography of D. melanogaster, and identified widespread signals of ad

SUBMITTER: Chen J 

PROVIDER: S-EPMC11023512 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature