Bursts from the past: Intrinsic properties link a network model to zebra finch song.

ABSTRACT: Neuronal intrinsic excitability is a mechanism implicated in learning and memory that is distinct from synaptic plasticity. Prior work in songbirds established that intrinsic properties (IPs) of premotor basal-ganglia-projecting neurons (HVC_X) relate to learned song. Here we find that temporal song structure is related to specific HVC_X IPs: HVC_X from birds who sang longer songs including longer invariant vocalizations (harmonic stacks) had IPs that reflected increased post-inhibitory rebound. This suggests a rebound excitation mechanism underlying the ability of HVC_X neurons to integrate over long periods of time throughout the song and represent sequence information. To explore this, we constructed a network model of realistic neurons showing ho

SUBMITTER: Medina ND 

PROVIDER: S-EPMC11118566 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature