Tolerability and blinding of high-definition transcranial direct current stimulation among older adults at intensities of up to 4 mA per electrode.

ABSTRACT:

Background

Few studies have investigated tolerability, blinding, and double-blinding of High-Definition transcranial Direct Current Stimulation (HD-tDCS) at amplitudes above 2 milliamps (mA).

Objective

We examined a) tolerability of HD-tDCS during stimulation sessions and b) blinding and double blinding of participants and study team members.

Methods

Data from a mixed neurologic sample of 292 older adults were pooled from 3046 HD-tDCS sessions (2329 active; 717 sham). Per electrode amplitudes ranged from 1 mA to 4 mA with total currents up to 10 mA. Participants completed a standardized sensation (tolerability) questionnaire after each session. Participants and study team members stated whether the participant received active or sham stimulation at the end of various

SUBMITTER: El Jamal C 

PROVIDER: S-EPMC11218548 | biostudies-literature | 2023 Sep-Oct

REPOSITORIES: biostudies-literature