Detectability of intracranial vessel wall atherosclerosis using black-blood spectral CT: a phantom and clinical study.

ABSTRACT:

Background

Computed tomography (CT) is the usual modality for diagnosing stroke, but conventional CT angiography reconstructions have limitations.

Methods

A phantom with tubes of known diameters and wall thickness was scanned for wall detectability, wall thickness, and contrast-to-noise ratio (CNR) on conventional and spectral black-blood (SBB) images. The clinical study included 34 stroke patients. Diagnostic certainty and conspicuity of normal/abnormal intracranial vessels using SBB were compared to conventional. Sensitivity/specificity/accuracy of SBB and conventional were compared for plaque detectability. CNR of the wall/lumen and quantitative comparison of remodeling index, plaque burden, and eccentricity were obtained for SBB imaging and high-resolution magnetic reson

SUBMITTER: Zhang F 

PROVIDER: S-EPMC11219652 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature