Increasing diversity in clinical trials: demographic trends at the National Cancer Institute, 2005-2020.

ABSTRACT:

Background

We described participant demographics for National Cancer Institute (NCI) clinical trials at the clinical center (NCI-CC participants) of the National Institutes of Health to identify enrollment disparities.

Methods

We analyzed NCI-CC data from 2005 to 2020, calculated enrollment fractions, compared with the US cancer population represented by the Surveillance, Epidemiology, and End Results cancer incidence data (2018) and the Cancer in North America database (2018), and compared further with clinical trial disparities data from the NCI Community Oncology Research Program and National Clinical Trials Network (2005-2019), and from ClinicalTrials.gov (2003-2016).

Results

NCI-CC (38 531 participants) had higher enrollment fractions for older adults (8.5%), mal

SUBMITTER: Choradia N 

PROVIDER: S-EPMC11223850 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature