Preschool impulse oscillometry predicts active asthma and impaired lung function at school age.

ABSTRACT:

Background

Asthmatic symptoms often start during early childhood. Impulse oscillometry (IOS) is feasible in preschool children who may be unable to reliably perform spirometry measurements.

Objective

We sought to evaluate the use of IOS in a multicenter, multiethnic high-risk asthma cohort titled the Vitamin D Antenatal Asthma Reduction Trial.

Methods

The trial recruited pregnant women whose children were followed from birth to age 8 years. Lung function was assessed with IOS at ages 4, 5, and 6 years and spirometry at ages 5, 6, 7, and 8 years. Asthma status, respiratory symptoms, and medication use were assessed with repeated questionnaires from birth to age 8 years.

Results

In total, 220 children were included in this secondary analysis. Recent respiratory s

SUBMITTER: Knihtila HM 

PROVIDER: S-EPMC11227409 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature