Long-term Health Outcomes of New Persistent Opioid Use After Gastrointestinal Cancer Surgery.

ABSTRACT:

Background

New persistent opioid use (NPOU) after surgery has been identified as a common complication. This study sought to assess the long-term health outcomes among patients who experienced NPOU after gastrointestinal (GI) cancer surgery.

Methods

Patients who underwent surgery for hepato-pancreato-biliary and colorectal cancer between 2007 and 2019 were identified using the Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked database. Mixed-effect multivariable logistic regression and Cox proportional hazard models were used to estimate the risk of mortality and hospital visits related to falls, respiratory events, or pain symptoms.

Results

Among 15,456 patients who underwent GI cancer surgery, 967(6.6%) experienced NPOU. Notably, the patients at ris

SUBMITTER: Khalil M 

PROVIDER: S-EPMC11236845 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature