Blood Pressure Effect of Traffic-Related Air Pollution : A Crossover Trial of In-Vehicle Filtration.

ABSTRACT:

Background

Ambient air pollution, including traffic-related air pollution (TRAP), increases cardiovascular disease risk, possibly through vascular alterations. Limited information exists about in-vehicle TRAP exposure and vascular changes.

Objective

To determine via particle filtration the effect of on-roadway TRAP exposure on blood pressure and retinal vasculature.

Design

Randomized crossover trial. (ClinicalTrials.gov: NCT05454930).

Setting

In-vehicle scripted commutes driven through traffic in Seattle, Washington, during 2014 to 2016.

Participants

Normotensive persons aged 22 to 45 years (n = 16).

Intervention

On 2 days, on-road air was entrained into the vehicle. On another day, the vehicle was equipped with high-efficiency particulate

SUBMITTER: Young MT 

PROVIDER: S-EPMC11259360 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature