Safety and Efficacy of AlphaWave^® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.

ABSTRACT:

Background

Prolonged periods of stress may lead to negative health consequences. AlphaWave^® L-Theanine was safe and efficacious during an acute stress challenge. However, double-blind, placebo-controlled clinical trials investigating the longer term effects of L-theanine supplementation on stress are warranted.

Methods

Thirty healthy adults (18-65 years) with moderate stress were randomized to AlphaWave^® L-Theanine (400 mg L-theanine/day) or placebo (n = 15/group) for 28 days. Stress was assessed by salivary cortisol, Perceived Stress Scale (PSS) and Depression, Anxiety and Stress Scale-21; sleep was assessed by the Healthy People Sleep Quality Index and actigraphy device; cognition was assessed by Computerized Mental Performance Assessment System; mood

SUBMITTER: Moulin M 

PROVIDER: S-EPMC11263523 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature