Obesity and Early-Onset Breast Cancer and Specific Molecular Subtype Diagnosis in Black and White Women: NIMHD Social Epigenomics Program.

ABSTRACT:

Importance

Epidemiologic data suggest an association of obesity with breast cancer (BC); however, obesity's contribution to early onset and risk of diagnosis with specific molecular subtypes by race is uncertain.

Objective

To examine the race-specific association of body mass index with early onset and diagnosis of specific molecular subtypes.

Design, setting, and participants

This retrospective cohort study included patients with BC diagnosed between October 1, 2017, and March 31, 2022, at 3 University of South Alabama Mitchell Cancer Institute clinics. Participants were also prospectively enrolled for serum leptin measurement.

Main outcomes and measures

The primary outcome was age at BC onset and specific subtype diagnosis. The secondary outcome was race-spec

SUBMITTER: Sudan SK 

PROVIDER: S-EPMC11287389 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature