Macroscale brain states support the control of semantic cognition.

ABSTRACT: A crucial aim in neuroscience is to understand how the human brain adapts to varying cognitive demands. This study investigates network reconfiguration during controlled semantic retrieval in differing contexts. We analyze brain responses to two semantic tasks of varying difficulty - global association and feature matching judgments - which are contrasted with non-semantic tasks on the cortical surface and within a whole-brain state space. Demanding semantic association tasks elicit activation in anterior prefrontal and temporal regions, while challenging semantic feature matching and non-semantic tasks predominantly activate posterior regions. Task difficulty also modulates activation along different dimensions of functional organization, suggesting different mechanisms of cognitive contr

SUBMITTER: Wang X 

PROVIDER: S-EPMC11294576 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature