Mass and Stiffness Deconvolution in Nanomechanical Resonators for Precise Mass Measurement and In Vivo Biosensing.

ABSTRACT: Nanomechanical sensors, due to their small size and high sensitivity to the environment, hold significant promise for various sensing applications. These sensors enable rapid, highly sensitive, and selective detection of biological and biochemical entities as well as mass spectrometry by utilizing the frequency shift of nanomechanical resonators. Nanomechanical systems have been employed to measure the mass of cells and biomolecules and study the fundamentals of surface science such as phase transitions and diffusion. Here, we develop a methodology using both experimental measurements and numerical simulations to explore the characteristics of nanomechanical resonators when the detection entities are absorbed on the cantilever surface and quantify the mass, density, and Young's modulus of

SUBMITTER: Bhattacharya G 

PROVIDER: S-EPMC11308922 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature