Defining the role of surgery for patients with multiple brain metastases.

ABSTRACT:

Purpose

To better define the role of surgery, we investigated survival and functional outcomes in patients with multiple brain metastases.

Methods

Pertinent clinical and radiological data of 131 consecutive patients (156 surgeries) were analyzed retrospectively.

Results

Surgical indications included mass effect (84.6%) and need for tissue acquisition (44.9%, for molecularly informed treatment: 10 patients). Major (i.e. CTCAE grade 3-5) neurological, surgical and medical complication were observed in 6 (3.8%), 12 (7.7%), and 12 (7.7%) surgical cases. Median preoperative and discharge KPS were 80% (IQF: 60-90%). Median overall survival (mOS) was 7.4 months. However, estimated 1 and 2 year overall survival rates were 35.6% and 25.1%, respectively. Survival was dismal (i.

SUBMITTER: Ersoy TF 

PROVIDER: S-EPMC11341766 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature