Obstetric Outcomes in Women on Lithium: A Systematic Review and Meta-Analysis.

ABSTRACT: Background/Objectives: Lithium taken during pregnancy was linked in the past with increased risk for foetal/newborn malformations, but clinicians believe that it is worse for newborn children not to treat the mothers' underlying psychiatric illness. We set to review the available evidence of adverse foetal outcomes in women who received lithium treatment for some time during their pregnancy. Methods: We searched four databases and a register to seek papers reporting neonatal outcomes of women who took lithium during their pregnancy by using the appropriate terms. We adopted the PRISMA statement and used Delphi rounds among all the authors to assess eligibility and the Cochrane Risk-of-Bias tool to evaluate the RoB of the included studies. Results: We found 28 eligible

SUBMITTER: Callovini T 

PROVIDER: S-EPMC11355283 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature