Racial distribution of molecularly classified brain tumors.

ABSTRACT:

Background

In many cancers, specific subtypes are more prevalent in specific racial backgrounds. However, little is known about the racial distribution of specific molecular types of brain tumors. Public data repositories lack data on many brain tumor subtypes as well as diagnostic annotation using the current World Health Organization classification. A better understanding of the prevalence of brain tumors in different racial backgrounds may provide insight into tumor predisposition and development, and improve prevention.

Methods

We retrospectively analyzed the racial distribution of 1709 primary brain tumors classified by their methylation profiles using clinically validated whole genome DNA methylation. Self-reported race was obtained from medical records. Our cohort inc

SUBMITTER: Fang CS 

PROVIDER: S-EPMC11362849 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature