Association of longitudinal changes in 24-h blood pressure level and variability with cognitive decline.

ABSTRACT:

Objective

A high office blood pressure (BP) is associated with cognitive decline. However, evidence of 24-h ambulatory BP monitoring is limited, and no studies have investigated whether longitudinal changes in 24-h BP are associated with cognitive decline. We aimed to test whether higher longitudinal changes in 24-h ambulatory BP measurements are associated with cognitive decline.

Methods

We included 437 dementia-free participants from the Maracaibo Aging Study with prospective data on 24-h ambulatory BP monitoring and cognitive function, which was assessed using the selective reminding test (SRT) and the Mini-Mental State Examination (MMSE). Using multivariate linear mixed regression models, we analyzed the association between longitudinal changes in measures of 24-h ambula

SUBMITTER: Melgarejo JD 

PROVIDER: S-EPMC11449671 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature