Assessing the accuracy of CMRtools software for diagnosing liver iron overload in thalassemia patients: influencing factors and optimisation strategies.

ABSTRACT:

Background

CMRtools is a software package that can be used to measure T2* values to diagnose liver iron overload, however, its accuracy in terms is affected by multiple factors, including goodness-of-fit (R² value), the number of echo time (TE) images, and the liver iron concentration (LIC). To investigate the effects of the R² value, the number of TE images, and the LIC on the accuracy of CMRtools software for measuring T2* values to diagnose liver iron overload (LIO).

Materials and methods

CMRtools software was used to measure liver T2* values among 108 thalassemia patients via the truncation method, and the R² values, the number of TE images, and T2* values were recorded. These values were subsequently converted into liver iron concentrati

SUBMITTER: Luo C 

PROVIDER: S-EPMC11449772 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature