Primary lung signet-ring cell carcinoma: a national analysis.

ABSTRACT:

Background

Primary lung signet-ring cell carcinoma (LSRCC) is a rare form of aggressive lung cancer whose clinical features remain inadequately discerned. The objective of this study was to evaluate the clinicopathological characteristics and independent prognostic factors of primary LSRCC.

Methods

Overall survival (OS) of patients with LSRCC, lung adenocarcinoma (LAC), and lung mucinous adenocarcinoma (LMAC) in the National Cancer Database from 2004 to 2018 was evaluated using Kaplan-Meier and multivariable Cox proportional hazards modeling. Independent prognostic indicators for patients with LSRCC were determined using multivariable Cox proportional hazards analysis.

Results

A total of 1,705 LSRCC, 504,006 LAC, and 15,883 LMAC patients were included in our analysis.

SUBMITTER: Mansur A 

PROVIDER: S-EPMC11494572 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature