Facial aging, cognitive impairment, and dementia risk.

ABSTRACT:

Background

Facial aging, cognitive impairment, and dementia are all age-related conditions. However, the temporal relation between facial age and future risk of dementia was not systematically examined.

Objectives

To investigate the relationship between facial age (both subjective/perceived and objective) and cognitive impairment and/or dementia risk.

Methods

The study included 195,329 participants (age ≥ 60 y) from the UK Biobank (UKB) with self-perceived facial age and 612 participants from the Nutrition and Health of Aging Population in China Project (NHAPC) study (age ≥ 56 y) with objective assessment of facial age. Cox proportional hazards model was used to prospectively examine the hazard ratios (HRs) and their 95% confidence intervals (CIs) of self-perceived fa

SUBMITTER: Xu X 

PROVIDER: S-EPMC11539626 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature