A Ru-Based Complex for Sustainable One-Pot Tandem Aerobic Oxidation-Knoevenagel Condensation Reactions.

ABSTRACT: Our novel binuclear complex-anchored Ru(III) catalyst, designed and assembled by sonicating 2,2'-(4,6-dihydroxy-1,3-phenylene)bis(1H-benzo[d]imidazole-4-carboxylic acid), Ru(DMSO)₄Cl₂ and 4-methylpyridine, demonstrates remarkable efficiency and selectivity. It promotes one-pot reactions, including active methylenes and benzyl alcohols in water, via a tandem aerobic oxidation/Knoevenagel condensation process, yielding benzylidene malononitrile in excellent yields. The catalyst's ability to oxidize benzyl alcohols to aldehydes, which then undergo Knoevenagel condensation with active methylenes, makes it a multifunctional catalyst. Notably, the catalyst can be successfully retrieved and recycled for five successive rounds with no significant decrease in cat

SUBMITTER: Arafa WAA 

PROVIDER: S-EPMC11547704 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature