CT-FFR by expanding coronary tree with Newton-Krylov-Schwarz method to solve the governing equations of CFD.

ABSTRACT:

Aims

A new model of computational fluid dynamics (CFD)-based algorithm for coronary CT angiography (CCTA)-derived fractional flow reserve (FFR) (CT-FFR) analysis by expanding the coronary tree to smaller-diameter lumen (0.8 mm) using Newton-Krylov-Schwarz (NKS) method to solve the three-dimensional time-dependent incompressible Navier-Stokes equations has been developed; however, the diagnostic performance of this new method has not been sufficiently investigated. The aim of this study was to determine the diagnostic performance of a novel CT-FFR technique by expanding the coronary tree in the CFD domain.

Methods and results

Six centres enrolled 338 symptomatic patients with suspected or known coronary artery disease (CAD) who prospectively underwent CCTA and FFR. Stenosis a

SUBMITTER: Guo W 

PROVIDER: S-EPMC11547952 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature