Prognostic value of β1 adrenergic receptor autoantibodies for microvascular obstruction in patients with STEMI with Post-PCI: A prospective cohort study.

ABSTRACT:

Backgrounds

Coronary microvascular obstruction (MVO) frequently occurs in patients with ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI), leading to poor prognosis. β₁ adrenergic receptor autoantibodies (β₁-AA) are present in various cardiovascular diseases and correlate with cardiac damage and dysfunction. However, whether β₁-AA is associated with the occurrence of MVO in patients with STEMI after PCI remains unclear.

Aims

To investigate the prognostic relationship between β₁-AA and the occurrence of MVO in patients with STEMI with post-PCI.

Methods

This prospective study included 403 patients with STEMI who underwent primary PCI. The patients were divided into MVO+ and M

SUBMITTER: Cao N 

PROVIDER: S-EPMC11615580 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature