Seroprevalence of SARS-CoV-2 antibodies among children receiving primary care in Toronto, Ontario.

ABSTRACT:

Objective

Characterizing the seroprevalence of SARS-CoV-2 antibodies in children is needed to optimize the COVID-19 public health response. We quantified the seroprevalence of SARS-CoV-2 infection-acquired antibodies and vaccine-acquired antibodies among children receiving primary care in Toronto, Canada.

Methods

We conducted a longitudinal cohort study between January 2021 and November 2022 in healthy children aged 0-16 years receiving primary care in Toronto. The primary and secondary outcomes were seroprevalence of SARS-COV-2 infection-acquired antibodies and vaccine-acquired antibodies ascertained from finger-prick dried blood spots. Samples were tested using an enzyme-linked immunosorbent assay for antibodies to full-length spike trimer and nucleocapsid. We explored soc

SUBMITTER: Aglipay M 

PROVIDER: S-EPMC11644124 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature