Estimated Vaccine Effectiveness for Respiratory Syncytial Virus-Related Lower Respiratory Tract Disease.

ABSTRACT:

Importance

Clinical trials have demonstrated high vaccine efficacy (VE) against lower respiratory tract disease (LRTD) but enrolled a smaller proportion of persons aged 75 years or older and those with comorbidities than seen in highest-risk populations in clinical practice settings. Additionally, VE against respiratory syncytial virus (RSV)-related hospitalizations and emergency department (ED) visits is not yet fully described.

Objective

To estimate Respiratory Syncytial Virus Prefusion F (RSVpreF) effectiveness in older adults.

Design, setting, and participants

This was a retrospective case-control study with a test negative design. Cases were adults aged 60 years or older with hospitalizations or ED visits at Kaiser Permanente of Southern California for LRTD from

SUBMITTER: Tartof SY 

PROVIDER: S-EPMC11645642 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature