C-C bond coupling with sp³ C-H bond via active intermediates from CO₂ hydrogenation.

ABSTRACT: Compared to the sluggish kinetics observed in methanol-mediated side-chain alkylation of methyl groups with sp³ C-H bonds, CO₂ hydrogenation emerges as a sustainable alternative strategy, yet it remains a challenge. Here, as far as we know, it is first reported that using CO₂ hydrogenation replacing methanol can conduct the side-chain alkylation of 4-methylpyridine (MEPY) over a binary metal oxide-zeolite Zn₄₀Zr₆₀O/CsX tandem catalyst (ZZO/CsX). This ZZO/CsX catalyst can achieve 19.6% MEPY single-pass conversion and 82% 4-ethylpyridine (ETPY) selectivity by using CO₂ hydrogenation, which is 6.5 times more active than methanol as an alkylation agent. The excellent catalytic performance is realized on the basis of the dual fun

SUBMITTER: Ma Q 

PROVIDER: S-EPMC11697012 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature